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To guarantee tight regulation, molecular machinery for the regulation of iron transporters exists in the form of the iron responsive element/iron regulatory protein (IRE/IRP) system

10.1007/s00424-011-1044-0 27 BesedovskyL.LangeT.HaackM

Nonetheless, from the several available data, it is possible to assert that the relationship between ROS and atrophy is well-grounded and future research clarifying the connections at the molecular level will be fundamental for the identification of molecular targets for therapeutic interventions (Figure 4)