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Nanobiotechnology-based strategies for crossing the blood-brain barrier

Meanwhile, CD38 inhibitor 78c verified this protective effect [42]

However, the bioavailability of oral glutathione is relatively low, as a significant portion may be broken down in the digestive tract before it can be absorbed into the bloodstream

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It has been demonstrated that PKM2 regulates the expression of pro-inflammatory cytokines, such as interleukin-1 beta (IL-1), by modulating the activity of hypoxia-inducible factor 1 alpha (HIF1), a key transcription factor involved in the inflammatory signaling pathway [26]