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10.1056/NEJMra1106180 N Engl J Med

While the treatment with Ru(II)-OH or NP2 slightly elevated the ROS levels inside the hypoxic cancer cells, the treatment with NP4 showed a strong enhancement of ROS

High resolution mass spectrometry of GSH (50 mM) in the presence of Ru(II)-OH (2 mM) were directly conducted after preparation and after incubation for 12 h