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It modulates neurotransmitters such as serotonin and dopamine and may increase levels of BDNF, a key molecule associated with synaptic plasticity and emotion regulation

Supplementary material The Supplementary Material for this article can be found online at: References 1 AdrianL.LenskiM.TdterK.HeerenJ.BhmM.LaufsU

Therefore, current antiinflammatory therapies in PCOS, though not explicitly designed for NET inhibition, may indirectly suppress neutrophil activation, NET formation, and subsequent tissue injuryforming a practical backdoor into the neutrophilNET therapeutic space