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J Clin Oncol J Am Soc Clin Oncol

The pathway starts with epoxidation of fumaric acid to the warhead (2 S ,3 S )- trans -epoxysuccinic acid with an Fe(II)/-ketoglutarate-dependent oxygenase, followed by successive condensation with an l-amino acid by an adenosine triphosphate grasp enzyme and with an amine by the fungal example of amide bond synthetase

Microvascular Research (116), 50-56

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