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Regardless of oxygen availability, tumor cells primarily rely on glucose consumption and lactate production for energy, a phenomenon known as the Warburg effect or aerobic glycolysis ( The review first outlines the functions of different subpopulations of T cells in peripheral neuropathic pain arising from persistent nerve injury

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This shift is associated with reduced cellularity and significant thymus involution[167, 168]

The first randomised trial for GBS evaluated PE versus supportive treatment alone and was published in 1984

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corpus callosum in CAE), in the former, a deliberately orchestrated primary autoimmune process directed at myelin antigens results in lymphocytic infiltration, secondary injury to white matter and a universal innate response, whereas in CAE, where the primary insult is a biochemical one deliberately targeting intrinsic CNS myelin, following immune stimulation, the resulting lesion is pathologically similar (Day, 2005