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The conditions complex pathology, involving both inflammation and structural changes to the joint capsule, may respond differently depending on the stage when treatment begins

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Hou demonstrated that autophagy induces ferroptosis through the degradation of ferritin in fibroblasts and cancer cells ( 3.1.2 ROS imbalance plays an important role in ferroptosis Lipid peroxidation is the fundamental root cause of ferroptosis, and since lipids make up the majority of cell membranes, they are also the dominating targets of ROS