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Description

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M.SuttonN

Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity

Results Cancer cells, including melanoma, depend on de novo metabolic synthesis pathways to sustain high proliferation levels Consensus metabolic networks were reconstructed at the genome-scale for the TCGA, SKCM and IN-HOUSE datasets to capture metabolic alterations in cancer in general and in melanoma specifically