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10.1093/pcp/pcn196 8 ChakiM.ValderramaR.Fernndez-OcaaA

Dithiothreitol, which is commonly used to minimize the viscosity of sputum samples, is a strong reducing agent and concentrations above 0.001% artificially increase total glutathione concentrations while decreasing GSSG (27)

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The form, dose, and delivery method determine how much glutathione reaches the intestinal lumen versus systemic circulation