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10.1172/JCI168554 16 BharatV.DurairajA

Mitochondrial GSH (mGSH) regulates mitochondrial ATP production by modifying critical protein sulfhydryl redox states that consequently influence nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2) generation and electron flow in the electron transport chain (ETC)

DNA (~1g) was treated with ribonuclease A (Sigma) to remove any contaminating RNA and digested into component nucleotides by sequential treatments with nuclease P1, snake venom phosphodiesterase, and alkaline phosphatase